Biosensors: Magnets tackle kinetic questions.
Shawn P. Mulvaney
Nature Nanotechnology 6, 266 (2011)
Quantification of protein interactions and solution transport using high-density GMR sensor arrays
Richard S. Gaster, Liang Xu, Shu-Jen Han , Robert J. Wilson , Drew A. Hall , Sebastian J. Osterfeld , Heng Yu ,and Shan X. Wang
Nature Nanotechnology 6, 314 (2011)
Shawn P. Mulvaney
Nature Nanotechnology 6, 266 (2011)
Quantification of protein interactions and solution transport using high-density GMR sensor arrays
Richard S. Gaster, Liang Xu, Shu-Jen Han , Robert J. Wilson , Drew A. Hall , Sebastian J. Osterfeld , Heng Yu ,and Shan X. Wang
Nature Nanotechnology 6, 314 (2011)
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| GMR sensors can also be used to detect biomolecules that have been labelled with magnetic beads (left). Here one of the four antibodies (blue) attached to a magnetic bead (red) binds to a protein antigen (yellow) immobilized on top of a GMR sensor in a proteomic microarray. The change in the resistance of the GMR wire caused by the magnetic field of the bead allows the kinetics of the protein–antibody interaction to be studied. |
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